Sorin Group’s cardiopulmonary machine C5 adopts a modular structure. It is designed for performing cardiac pumping and replacing pulmonary function in time-limited cardiac surgeries. The blood filters through the needle tubing in vitro and then filters back into the body. The design of this high-risk medical device is based on the rigorous ergonomics that satisfies the function and the structure design after deep thinking. The stainless steel material, smooth and concise design of the surface, and minimizing of the whole machine, are the extreme embodiment of satisfying the needs of operating rooms. Also, the two distinct layouts of the central workstation meet the requirements of not only surgeons but also assistants perfectly in both function and height. The location and logical details of the workstation pass usability evaluation and design. The pump in the low protected area is the operating unit of devices, while the front end facing the surgeon is the human-machine interactive control and display unit.